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Pazopanib-induced hyperbilirubinemia is associated with Gilbert's syndrome UGT1A1 polymorphism

✍ Scribed by Xu, C-F; Reck, B H; Xue, Z; Huang, L; Baker, K L; Chen, M; Chen, E P; Ellens, H E; Mooser, V E; Cardon, L R

Book ID
110000447
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
431 KB
Volume
102
Category
Article
ISSN
0007-0920

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## Abstract Several lines of evidence suggest that oxidative stress plays a role in the mechanisms of action of methamphetamine (MAP) in the human brain. Given the role of glutathione __S__‐transferases (GSTs) in the protection against oxidative stress, genes encoding the GSTs have been considered