✦ LIBER ✦

Pazopanib, a multitargeted tyrosine kinase inhibitor, reduces diabetic retinal vascular leukostasis and leakage

✍ Scribed by Ashish Thakur; Robert I. Scheinman; Vidhya R. Rao; Uday B. Kompella

Book ID: 116760981
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 278 KB
Volume: 82
Category: Article
ISSN: 0026-2862
DOI: 10.1016/j.mvr.2011.09.001

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

ChemInform Abstract: Polypharmacology of

ChemInform Abstract: Polypharmacology of Sulfonamides: Pazopanib, a Multitargeted Receptor Tyrosine Kinase Inhibitor in Clinical Use, Potently Inhibits Several Mammalian Carbonic Anhydrases.

✍ Winum, Jean-Yves; Maresca, Alfonso; Carta, Fabrizio; Scozzafava, Andrea; Supuran 📂 Article 📅 2012 🏛 John Wiley and Sons ⚖ 21 KB

Discovery of a novel class of targeted k

Discovery of a novel class of targeted kinase inhibitors that blocks protein kinase C signaling and ameliorates retinal vascular leakage in a diabetic rat model

✍ Stephan Grant; Phong Tran; Qin Zhang; Aihua Zou; Dac Dinh; Jordan Jensen; Sue Zh 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 918 KB

Celecoxib, a selective cyclooxygenase-2

Celecoxib, a selective cyclooxygenase-2 inhibitor, inhibits retinal vascular endothelial growth factor expression and vascular leakage in a streptozotocin-induced diabetic rat model

✍ Surya P. Ayalasomayajula; Uday B. Kompella 📂 Article 📅 2003 🏛 Elsevier Science 🌐 English ⚖ 232 KB

A Protein Tyrosine Kinase Inhibitor, Ima

A Protein Tyrosine Kinase Inhibitor, Imatinib Mesylate (Gleevec), Improves Erectile and Vascular Function Secondary to a Reduction of Hyperglycemia in Diabetic Rats

✍ Serap Gur; Philip J. Kadowitz; Wayne J.G. Hellstrom 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 514 KB

PTK787/ZK222584, a tyrosine kinase inhib

PTK787/ZK222584, a tyrosine kinase inhibitor of vascular endothelial growth factor receptor, reduces uptake of the contrast agent GdDOTA by murine orthotopic B16/BL6 melanoma tumours and inhibits their growth in vivo

✍ Markus Rudin; Paul M. J. McSheehy; Peter R. Allegrini; Martin Rausch; Diana Baum 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 793 KB

## Abstract Assessment of tumour vascularity may characterize malignancy as well as predict responsiveness to anti‐angiogenic therapy. Non‐invasive measurement of tumour perfusion and blood vessel permeability assessed as the transfer constant, __K__^trans^, can be provided by dynamic contrast‐enha