𝔖 Bobbio Scriptorium
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Paxβ: a novel family of lophotrochozoan Pax genes

✍ Scribed by Matthew Schmerer; Robert M. Savage; Marty Shankland


Book ID
109085116
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
990 KB
Volume
11
Category
Article
ISSN
1520-541X

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Aniridia is an autosomal dominant panocular disorder, characterized by hypoplasia of the iris. It is caused by mutations in the PAX6 gene. This gene encodes a 422-amino acid transcription factor. This protein includes paired and homeo domains, which bind DNA and a proline-serine and threonine-rich P