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PAX3/7–FOXO1fusion status in older rhabdomyosarcoma patient population by fluorescent in situ hybridization

✍ Scribed by Sarah N. Dumont; Alexander J. Lazar; Julia A. Bridge; Robert S. Benjamin; Jonathan C. Trent

Book ID
106124493
Publisher
Springer-Verlag
Year
2011
Tongue
English
Weight
711 KB
Volume
138
Category
Article
ISSN
1432-1335

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✍ Jaclyn A. Biegel; Lynn M. Nycum; Virginia Valentine; Frederic G. Barr; David N. 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 600 KB

Cytogenetic studies of the pediatric solid tumor alveolar rhabdomyosarcoma have demonstrated the presence of a consistent chromosomal translocation, t(2 I3)(q35;q 14). We recently identified PAX3 and FKHR as the genes on chromosomes 2 and I 3, respectively, that are juxtaposed by this translocation.