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Pax3 regulates Wnt1 expression via a conserved binding site in the 5′ proximal promoter

✍ Scribed by Benjamin T. Fenby; Vassiliki Fotaki; John O. Mason

Book ID: 116272429
Publisher: Elsevier
Year: 2008
Tongue: English
Weight: 461 KB
Volume: 1779
Category: Article
ISSN: 1874-9399
DOI: 10.1016/j.bbagrm.2007.11.008

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## Abstract VHL is the causative gene for von Hippel‐Lindau disease and sporadic clear cell renal cancer. It has been shown that pVHL can suppress the expression of certain genes that are overexpressed in renal carcinomas. One such gene is that encoding the potent mitogen and chemoattractant, plate