PATTERNS OF PROGRESSION IN PROSTATE CANCER
β Scribed by JohnE. Mcneal; RobertA. Kindrachuk; FuadS. Freiha; DavidG. Bostwick; EliseA. Redwine; ThomasA. Stamey
- Book ID
- 118145292
- Publisher
- The Lancet
- Year
- 1986
- Tongue
- English
- Weight
- 535 KB
- Volume
- 327
- Category
- Article
- ISSN
- 0140-6736
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π SIMILAR VOLUMES
Genetic alterations in primary prostate cancer (CaP) have been extensively studied, yet little is known about the genetic mechanisms underlying progression of primary CaP to metastatic prostate cancer. As a result, it is not possible to distinguish clinically indolent localized disease from potentia
## Abstract When prostate cancer is first detected it generally is dependent on the presence of androgens for growth, and responds to androgen ablation therapies. However, the disease often recurs in a disseminated and apparently androgen independent (AI) form, and in this state is almost invariabl