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Patterns of meiotic double-strand breakage on native and artificial yeast chromosomes

โœ Scribed by Shoshana Klein; Drora Zenvirth; Vardit Dror; Arnold B. Barton; David B. Kaback; Giora Simchen


Book ID
110548059
Publisher
Springer
Year
1996
Tongue
English
Weight
309 KB
Volume
105
Category
Article
ISSN
0009-5915

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## Abstract Both somatic and meiotic recombinations involve the repair of DNA double strand breaks (DSBs) that occur at preferred locations in the genome. Improper repair of DSBs during either mitosis or meiosis can lead to mutations, chromosomal aberration such as translocations, cancer, and/or ce