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Patterns of cortical thickness and surface area in early Parkinson's disease

✍ Scribed by Thomas Jubault; Jean-François Gagnon; Sherif Karama; Alain Ptito; Anne-Louise Lafontaine; Alan C. Evans; Oury Monchi


Book ID
119331816
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
310 KB
Volume
55
Category
Article
ISSN
1053-8119

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## Abstract Neurodegeneration in clinically manifest Parkinson's disease affects the substantia nigra pars compacta, and gradually spreads to the limbic cortices and the neocortex. We used MRI imaging coupled with automated surface reconstruction and segmentation methods to examine cortical thickne