𝔖 Bobbio Scriptorium
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Patterning the pharyngeal arches

✍ Scribed by Anthony Graham; Alexa Smith

Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
186 KB
Volume
23
Category
Article
ISSN
0265-9247

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✦ Synopsis

The presence of a muscularised pharynx with skeletal support is a fundamental vertebrate characteristic. Developmentally, the pharynx arises from the pharyngeal arches on either side of the head of vertebrate embryos. The development of the pharyngeal arches is complex involving a number of disparate embryonic populations, ectoderm, endoderm, neural crest and mesoderm, which must be co-ordinated to generate the components and overall identity of each of the arches. Previous studies suggested that it is the neural crest that plays a pivotal role in patterning the pharyngeal arches. It is now also becoming clear, however, that there are crest-independent patterning mechanisms. Therefore, pharyngeal arch patterning is more complex than was previously believed and there must be an integration of crest-dependent and -independent patterning mechanisms. BioEssays 23:54-61, 2001.

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