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Patterned high-frequency stimulation induces a form of long-term depression dependent on GABAA and mACh receptors in the hippocampus

✍ Scribed by Zhu, Y.-Y.; Jing, L.; Duan, T.-T.; Yuan, Q.; Cao, J.; Zhou, Q.-X.; Xu, L.


Book ID
122659437
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
947 KB
Volume
250
Category
Article
ISSN
0306-4522

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Low frequency-induced short-term synaptic plasticity was investigated in hippocampal slices with 60-electrode recording array. Remarkably, the application of low-frequency stimulation (1 Hz) for a short duration (3-5 min) resulted in the induction of a slow-onset longterm potentiation (LTP) in the i