Patterned Entry and Egress by Epstein–Barr Virus in Polarized CR2-Positive Epithelial Cells
✍ Scribed by James Chodosh; Yan-jun Gan; Virgil P. Holder; John W. Sixbey
- Book ID
- 112272368
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 341 KB
- Volume
- 266
- Category
- Article
- ISSN
- 0042-6822
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Normal nasopharyngeal tissues from 23 individuals who died of causes unrelated to the upper respiratory system and had no evidence of Epstein-Barr virus (EBV)-related diseases were studied using in situ hybridisation (ISH) and immunohistochemistry for the detection of EBV RNA and expression of EBV p
## Abstract Epstein‐Barr virus (EBV) is closely associated with nasopharyngeal carcinoma (NPC), a common cancer in Hong Kong. The EBV‐encoded LMP1 protein is believed to play an important role in cell transformation. We have previously identified a prevalent LMP1 variant (2117‐LMP1) that is express