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Pattern Recognition Analysis of Proteins Using DNA-Decorated Catalytic Gold Nanoparticles

✍ Scribed by Yang, Xiafeng; Li, Jiang; Pei, Hao; Li, Di; Zhao, Yun; Gao, Jimin; Lu, Jianxin; Shi, Jiye; Fan, Chunhai; Huang, Qing


Book ID
120207575
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
674 KB
Volume
9
Category
Article
ISSN
1613-6810

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We present a method based on surface-enhanced Raman spectroscopy and exploiting a protein-protein recognition process able to detect thrombin at subpicomolar concentrations. Gold nanoparticles (NPs) were capped with a bifunctional molecule capable of forming a covalent link with the aromatic residue