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Pattern of parvovirus B19 infection during different trimesters of pregnancy in Kuwait

✍ Scribed by Ma'asoumah Makhseed; Alexander Pacsa; Mohammad Abrar Ahmed; Sahar Sultan Essa


Publisher
Hindawi Publishing Corporation
Year
1999
Tongue
English
Weight
141 KB
Volume
7
Category
Article
ISSN
1064-7449

No coin nor oath required. For personal study only.

✦ Synopsis


Objective: Aims of this study were to determine the IgG and IgM seropositivity to parvovirus B19 during the three trimesters of pregnancy.

Methods: Initially, a total of 1,047 pregnant women were included in a prospective study. Blood samples were obtained from 343, 406 and 298 cases in the first, second and third trimesters, respectively. To study the incidence of seroconversion, a second sample of blood was obtained 2-4 weeks later from the first 100 cases, who were IgG and IgM negative in the first trimester.

Results: The seroprevalence of parvovirus B19 IgG and IgM was 53.3% and 2.2%, respectively. The incidence of seroconversion was 16.5%. The rate of fetal loss was 15.4% in patients with acute infection, all of which occurred in the first two trimesters.

Conclusions: The percentage of IgG positive cases is significantly higher in first and second trimesters compared to the third trimester. The seroconversion rate was 16.5%.


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