## Abstract The species‐specific relationships between trabecular morphology and osteocyte density were investigated in the femoral heads of 30 adult animals of five mammalian species (rat, rabbit, Rhesus monkey, pig, and cow). Our hypothesis is that osteocytes are mechanosensory cells and are invo
Pattern of bone loss of the proximal femur: A radiologic, densitometric, and histomorphometric study
✍ Scribed by Tadashi Kawashima; Hans K. Uhthoff
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 563 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0736-0266
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✦ Synopsis
Abstract
The pattern of bone loss in the proximal femur was studied in 141 cadaveric femora from 36 women and 39 men ranging from 27 to 89 years of age. Bone mineral density (BMD) of the femoral neck, greater trochanter, Ward's triangle, and tensile and compressive stress regions were measured by dual photon absorptiometry. Radiographs were graded by Singh's method. Histomorphometry of tensile and compressive trabecular areas was performed on ground midsection of the methylmethacrylate‐embedded whole proximal femur. Although Singh index had some correlation with BMD of the femoral neck, the various BMD measurements showed that all regions lost bone to the same extent; in particular, no selective bone loss was found at low stress regions (tensile trabeculae or Ward's triangle). Histomorphometry revealed that most of the trabecular bone loss of the proximal femur is attributable to a decrease in thickness of individual trabeculae.
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