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Pattern electroretinogram in glaucoma and ocular hypertension

✍ Scribed by M. Bach; A. Speidel-Fiaux

Publisher: Springer-Verlag
Year: 1989
Tongue: English
Weight: 444 KB
Volume: 73
Category: Article
ISSN: 0012-4486
DOI: 10.1007/bf00155035

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✦ Synopsis

We recorded the pattern electroretinogram (PERG) to small (0.8 ~ and very large (15 ~ check sizes in normal subjects, in patients with early-stage glaucoma, and in patients with ocular hypertension. In glaucoma, the PERG amplitude was reduced. This reduction was more prominent for a check size of 0.8 ~ as compared with 15 ~ stimuli and for high (16/s) as --~ompared with low (7.8/s) reversal rates. Using a discriminant analysis of the amplitudes for two different check sizes, we could distinguish the normal and the glaucoma groups with a specificity of 96% and a sensitivity of 91%. Of the ocular hypertension patients, 43% were classified as pathologic by the discriminant analysis. Thus multivariate analysis of the PERG may increase its diagnostic value.

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