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Patients with systemic lupus erythematosus, myositis, rheumatoid arthritis and scleroderma share activation of a common type I interferon pathway

✍ Scribed by Higgs, B. W.; Liu, Z.; White, B.; Zhu, W.; White, W. I.; Morehouse, C.; Brohawn, P.; Kiener, P. A.; Richman, L.; Fiorentino, D.; Greenberg, S. A.; Jallal, B.; Yao, Y.


Book ID
118128829
Publisher
BMJ Publishing Group
Year
2011
Tongue
English
Weight
501 KB
Volume
70
Category
Article
ISSN
0003-4967

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## Abstract ## Objective Gene‐expression studies have demonstrated increased expression of interferon (IFN)–inducible genes (IFIGs) in peripheral blood mononuclear cells (PBMCs) of many patients with systemic lupus erythematosus (SLE), with a predominant effect of type I IFN. This study examined t