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Patients with hypertrophic cardiomyopathy (HCM) and HCM gene carriers have attenuated myocardial oxygenation response to vasodilator stress - a potential mechanism for sudden cardiac death

✍ Scribed by Sairia Dass; Theodoros Karamitsos; Joseph Suttie; Emily Sever; Michael Jerosch-Herold; Hugh Watkins; Stefan Neubauer


Publisher
BioMed Central
Year
2012
Tongue
English
Weight
154 KB
Volume
14
Category
Article
ISSN
1097-6647

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✦ Synopsis


Tissue oxygenation response to adenosine stress in patients with hypertrophic cardiomyopathy (HCM) is blunted compared to athletes and normals. Myocardial tissue hypoxia during stress in HCM may potentially contribute to the increased exercise related deaths in this condition.