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Patient with pyruvate kinase deficiency developed acute myelogenous leukemia

✍ Scribed by Ryuji Leki; Shiro Miwa; Hisaichi Fujii; Shouji Kudoh; Hitoshi Kimura; Fumimaro Takaku

Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
452 KB
Volume
34
Category
Article
ISSN
0361-8609

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Ineffective erythropoiesis in the spleen
Ineffective erythropoiesis in the spleen of a patient with pyruvate kinase deficiency
✍ Shin Aizawa; Urara Kohdera; Masaki Hiramoto; Yutaka Kawakami; Ken-ichi Aisaki; Y πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 147 KB πŸ‘ 1 views

## Abstract In this study, possible adverse effects of pyruvate kinase (PK) deficiency on the maturation of erythroid progenitors were investigated. A 4‐year‐old Japanese girl with severe PK deficiency underwent splenectomy to reduce her need for blood transfusions. The spleen was examined a histol