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Pathway of urokinase-type plasminogen activator induction in the T47D and LLC-PK1, cell lines

โœ Scribed by D.A. Jans; C. Dierks-Ventling; B.A. Hemmings


Book ID
115892137
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
734 KB
Volume
172
Category
Article
ISSN
0014-4827

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In LLC-PK, porcine epithelial cells, the urokinase-type plasminogen activator (u-PA) mRNA and protein can be induced either by stimulation of the protein kinase C (PKC) pathway using a tumor promoter (PMA) or by stimulation of the protein kinase A (PKA) pathway with calcitonin SCT). By PKC, to LLC-P