Pathway of fructosan synthesis in leaf bases of Dactylis glomerata

Structure-Based Design and Synthesis of

Structure-Based Design and Synthesis of the First Weak Non-Phosphate Inhibitors for IspF, an Enzyme in the Non-Mevalonate Pathway of Isoprenoid Biosynthesis

✍ Corinne Baumgartner; Christian Eberle; François Diederich; Susan Lauw; Felix Roh 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 German ⚖ 583 KB

## Abstract In this paper, we describe the structure‐based design, synthesis, and biological evaluation of cytosine derivatives and analogues that inhibit IspF, an enzyme in the non‐mevalonate pathway of isoprenoid biosynthesis. This pathway is responsible for the biosynthesis of the C~5~ precursor