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Pathway-based genome-wide association analysis identified the biological importance of pyrimidine metabolism pathway contributing to osteoporosis

✍ Scribed by Hao He; Shu-feng Lei; Feng Zhang; Jian Li; Yong-jun Liu; Qing Tian; Hong-wen Deng

Book ID
116323696
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
65 KB
Volume
47
Category
Article
ISSN
8756-3282

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Wrist fracture is not only one of the most common osteoporotic fractures but also a predictor of future fractures at other sites. Wrist bone mineral density (BMD) is an important determinant of wrist fracture risk, with high heritability. Specific genes underlying wrist BMD variation are largely unk