Pathophysiology of the basal ganglia and movement disorders: From animal models to human clinical applications

Neuroinflammation in the pathophysiology

Neuroinflammation in the pathophysiology of Parkinson's disease: Evidence from animal models to human in vivo studies with [11C]-PK11195 PET

✍ Anna L. Bartels; Klaus L. Leenders 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 111 KB

## Abstract Increasing evidence suggests that neuroinflammation is an active process in Parkinson's disease (PD) that contributes to ongoing neurodegeneration. PD brains and experimental PD models show elevated cytokine levels and up‐regulation of inflammatory‐associated factors as cyclo‐oxygenase‐