Pathophysiology of ANCA-Associated Small Vessel Vasculitis
โ Scribed by Cees G. M. Kallenberg
- Book ID
- 107554187
- Publisher
- Springer
- Year
- 2010
- Tongue
- English
- Weight
- 260 KB
- Volume
- 12
- Category
- Article
- ISSN
- 1523-3774
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The aetiology of primary systemic vasculitides remains unknown. Recent advances have been made in the understanding of relevant mechanisms of inยฏammation, particularly the role of the endothelium and interactions with inยฏammatory mediators and immune effector cells. In Wegener's granulomatosis and m
Clinical observations, including a report of neonatal vasculitis occurring in a child born from a mother with antineutrophil cytoplasmic antibody directed to myeloperoxidase (MPO-ANCA)-associated vasculitis, suggest a pathogenic role for ANCA. Such a role is supported by in vitro experimental data s