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Pathophysiology of acute graft-versus-host disease: recent advances

โœ Scribed by Yaping Sun; Isao Tawara; Tomomi Toubai; Pavan Reddy


Book ID
119383181
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
384 KB
Volume
150
Category
Article
ISSN
1931-5244

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Pathophysiology of acute graft-versus-ho
โœ Pavan Reddy ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 175 KB

Graft-versus-host disease (GVHD) has been the primary limitation to the wider application of allogeneic bone marrow transplantation (BMT). The pathophysiology of acute GVHD is complex and can be conceptualized to be a three-step process based on murine studies. In step 1, the conditioning regimen le