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Pathophysiology and treatment of type 2 diabetes: perspectives on the past, present, and future

✍ Scribed by Kahn, Steven E. (author);Cooper, Mark E. (author);Del Prato, Stefano (author)

Book ID
121414574
Publisher
Elsevier B.V.
Year
2014
Tongue
English
Weight
753 KB
Volume
383
Category
Article
ISSN
0140-6736

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Pathophysiology and treatment of type 2
Pathophysiology and treatment of type 2 diabetes: perspectives on the past, present, and future
✍ Kahn, Steven E. (author);Cooper, Mark E. (author);Del Prato, Stefano (author) πŸ“‚ Article πŸ“… 2014 πŸ› Elsevier B.V. 🌐 English βš– 753 KB

Glucose metabolism is normally regulated by a feedback loop including islet Ξ² cells and insulin-sensitive tissues, in which tissue sensitivity to insulin affects magnitude of Ξ²-cell response. If insulin resistance is present, Ξ² cells maintain normal glucose tolerance by increasing insulin output. On