Pathophysiological relationships between lower urinary tract symptoms and the prostate do not strengthen over time

✍ Scribed by Lee, Amanda J.; Garraway, W. Michael; Simpson, Richard J.

• Publisher: John Wiley and Sons
• Year: 1998
• Tongue: English
• Weight: 148 KB
• Volume: 37
• Category: Article
• ISSN: 0270-4137
• DOI: 10.1002/(sici)1097-0045(19980915)37:1<5::aid-pros2>3.0.co;2-h

✦ Synopsis

BACKGROUND. The aim of this survey was to examine the relationships among baseline prostate gland volume and changes in urinary symptomatology 3 years later. METHODS. A Scottish community-based cohort of 193 men aged 40-79 years who had prostate volume measured by transrectal ultrasound (TRUS) were followed-up at 3 years. RESULTS. Only baseline nocturia correlated with prostate volume (r = 0.202, P = 0.0057), although some relationships existed for the antero-posterior dimension of the prostate gland. More statistically significant relationships were evident for adenoma volume rather than prostate volume, but they still had relatively low correlations (range, 0.19-0.31). CONCLUSIONS. This study demonstrates the lack of relationships between prostate gland variables and lower urinary tract symptoms (LUTS). Those relationships that are statistically significant (at the P < 0.01 level) are weak, and only explain at most 9% of the total variation of prostate or adenoma volume or their dimensions.