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Pathophysiological Actions of Protease-Activated Receptors (PARs)

✍ Scribed by N. M. Pandya; S. M. Jain; D. D. Santani

Book ID
102006056
Publisher
John Wiley and Sons
Year
2007
Weight
11 KB
Volume
38
Category
Article
ISSN
0931-7597

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Protease activated receptors (PARs) compose a family of G protein signal transduction receptors activated by proteolysis. In this study, the susceptibility of PARs expressed on human keratinocytes and dermal fibroblasts to the human mast cell proteases tryptase and chymase was evaluated. PAR activat