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Pathology of familial breast cancer: differences between breast cancers in carriers of BRCA1 or BRCA2 mutations and sporadic cases

โœ Scribed by Michael R Stratton

Book ID
118560394
Publisher
The Lancet
Year
1997
Tongue
English
Weight
52 KB
Volume
349
Category
Article
ISSN
0140-6736

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โœ Irina V. Tereschenko; Victoria M. Basham; Bruce A.J. Ponder; Paul D.P. Pharoah ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 24 KB ๐Ÿ‘ 2 views

We have screened index cases from 25 Russian breast/ovarian cancer families for germ-line mutations in all coding exons of the BRCA1 and BRCA2 genes, using multiplex heteroduplex analysis. In addition we tested 22 patients with breast cancer diagnosed before age 40 without family history and 6 patie