Growth/differentiation factors (GDFs) play a significant role in numerous skeletal tissues and processes. Previous work using the brachypod mouse has suggested that GDF-5 affects Achilles tendon composition, ultrastructure, and material behavior, as well as tendon repair. The aim of the present stud
β¦ LIBER β¦
Pathologic changes of Achilles tendon in leptin-deficient mice
β Scribed by Jinfei Ji; Zuyu wang; Dongquan Shi; Xiang Gao; Qing Jiang
- Publisher
- Springer
- Year
- 2009
- Tongue
- English
- Weight
- 287 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0172-8172
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## Abstract Increasing evidence suggests that the growth/differentiation factors, GDFs 5, 6, and 7 in particular, may play a role in tendon and ligament biology. Mice with genetic mutations in __Gdf5__ have altered tendon composition and mechanical behavior, whereas animals with functional null mut
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