The first book on this young, highly dynamic, and expanding field.
This comprehensive, interdisciplinary text focuses on those pathogenic bacteria that are of high scientific and public health interest, yet which also display great potential for the development of new diagnostic, prophylactic and therapeutic procedures.
The authors cover all aspects of pathogenomics, including methods, genomics and applications. In addition, the ongoing development of genome, transcriptome, proteome and bioinformatic analyses of pathogenic microorganisms and their host interactions makes for a comprehensive introduction to the field of modern genomic analysis.
This result is invaluable to researchers and students wishing to gain a general overview of microbial functional genome analysis and pathogenesis, while also representing a good starting point for those new to the area.Content:
Chapter 1 Bioinformatics: Data Mining Among Genome Sequences (pages 1β19): Susanne Kneitz and Thomas Dandekar
Chapter 2 Transcriptome Analysis: Towards a Comprehensive Understanding of Global Transcription Activity (pages 21β41): Ben Sidders and Neil Stoker
Chapter 3 Physiological Proteomics of Bacillus subtilis and Staphylococcus aureus: Towards a Comprehensive Understanding of Cell Physiology and Pathogenicity (pages 43β68): Michael Hecker and Susanne Engelmann
Chapter 4 Impact of Genome Sequences on Mutational Analysis of Fungal and Bacterial Pathogens (pages 69β81): Vladimir Pelicic and Xavier Nassif
Chapter 5 Pathogenomics of Escherichia coli and Shigella Species (pages 83β108): Ulrich Dobrindt and Jorg Hacker
Chapter 6 Pathogenomics of Salmonella Species (pages 109β124): Helene Andrews?Polymenis and Andreas J. Baumler
Chapter 7 Pathogenomics of Enterococcus faecalis (pages 125β147): Janet M. Manson and Michael S. Gilmore
Chapter 8 Genomics of Streptococci (pages 149β173): Joseph J. Ferretti and W. Michael McShan
Chapter 9 Pathogenic Staphylococci: Lessons from Comparative Genomics (pages 175β210): Knut Ohlsen, Martin Eckart, Christian Huttinger and Wilma Ziebuhr
Chapter 10 Pathogenomics: Insights into Tuberculosis and Related Mycobacterial Diseases (pages 211β230): Alexander S. Pym, Stephen V. Gordon and Roland Brosch
Chapter 11 Genomes of Pathogenic Neisseria Species (pages 231β255): Christoph Schoen, Heike Claus, Ulrich Vogel and Matthias Frosch
Chapter 12 Genomics of Pathogenic Clostridia and Bacilli (pages 257β280): Armin Ehrenreich, Gerhard Gottschalk and Holger Bruggemann
Chapter 13 The Genomes of Pathogenic Bartonella Species (pages 281β300): Carolin Frank, Eva Berglund and Siv G. E. Andersson
Chapter 14 Pathogenomics of Gastric and Enterohepatic Helicobacter Species (pages 301β313): Sebastian Suerbaum, Sandra Schwarz and Christine Josenhans
Chapter 15 Genomics of the Opportunistic Pathogen Legionella pneumophila (pages 315β337): Christel Cazalet and Carmen Buchrieser
Chapter 16 Genomics of Listeria monocytogenes (pages 339β366): Michael Kuhn and Werner Goebel
Chapter 17 Genomics of Viruses (pages 367β388): Esteban Domingo, Alejandro Brun, Jose Ignacio Nunez, Juan Cristina, Carlos Briones and Cristina Escarmis
Chapter 18 Genomics of Pathogenic Fungi (pages 389β416): Gerwald A. Kohler, Alan Kuo, George Newport and Nina Agabian
Chapter 19 Genomics of Pathogenic Parasites (pages 417β444): Gabriele Pradel and Thomas James Templeton
Chapter 20 Model Host Systems: Tools for Comprehensive Analysis of HostβPathogen Interactions (pages 445β456): Michael Steinert and Gernot Glockner
Chapter 21 Expression Analysis of Human Genes During Infection (pages 457β479): Erwin Bohn and Ingo B. Autenrieth
Chapter 22 Pathogenomics: Application and New Diagnostic Tools (pages 481β504): Soren Schubert and Jurgen Heesemann
Chapter 23 The Search for New Antibiotics (pages 505β531): Harald Labischinski, Christoph Freiberg and Heike Brotz?Oesterhelt
Chapter 24 Reverse Vaccinology: Revolutionizing the Approach to Vaccine Design (pages 533β554): Laura Serino, Mariagrazia Pizza and Rino Rappuoli