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Pathogenicity of anti-DNA autoantibodies. Role for a DNA cross-reactive lupus associated membrane protein (LAMP)

โœ Scribed by Chen, Zhengyi; Li, Yongle; Lin, Shuhai; Wei, Meiping; Du, Fuyou; Ruan, Guihua


Book ID
121942521
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
82 KB
Volume
2
Category
Article
ISSN
0896-8411

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Lupus anti-DNA autoantibodies cross-reac
โœ Gustavo Mostoslavsky; Ruth Fischel; Nurit Yachimovich; Yuval Yarkoni; Eliezer Ro ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 417 KB

Anti-DNA autoantibodies are the hallmark of human and murine systemic lupus erythematosus (SLE), an autoimmune rheumatic disease of unknown etiology. Some of these antibodies are believed to be pathogenic for kidney tissue and to initiate immune glomerulonephritis. However, the mechanisms by which a