Pathogenic antibodies to coagulation factors. Part one: Factor VIII and Factor IX
β Scribed by P. Lollar
- Book ID
- 109148433
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 228 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1538-7933
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Eight patients with inhibitors to factor VIII (4 hemophilia A and 4 nonhemophilic) were treated with recombinant activated factor VII (rFVIIa) to control severe abdominal bleeding. The recombinant factor was supplied under an open-label, emergency-use program to patients previously unresponsive to o
## Abstract The murine monoclonal antibodies ESH2, ESH4, ESH5, and ESH8 specifically bind and inhibit the procoagulant activity of human coagulation factor VIII (FVIII). They are frequently used as a model of inhibitors which are raised against injected FVIII in about 25% of hemophiliacs as a serio