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Pathogenesis of Shiga toxin-induced hemolytic uremic syndrome

โœ Scribed by Patricio E. Ray; Xue-Hui Liu

Publisher
Springer
Year
2001
Tongue
English
Weight
280 KB
Volume
16
Category
Article
ISSN
0931-041X

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## Abstract ## Background Hemolytic uremic syndrome (HUS) is the main cause of acute renal failure in early childhood. Most cases are due to intestinal infections from __Escherichia coli__ strains (STEC) which produce by Shiga toxin (Stxs). Stx1 and Stx2 produced by STEC in the gut are absorbed in