Pathogenesis of nigral cell death in Parkinson's disease
β Scribed by Serge Przedborski
- Book ID
- 116820037
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 98 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1353-8020
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
A number of factors have been implicated in the pathogenesis of cell death in Parkinson's disease (PD). These include oxidative stress, mitochondrial dysfunction, inflammation, excitotoxicity, and apoptosis. While the precise pathogenic mechanism leading to neurodegeneration in PD is not known, ther
Neuronal loss in the substantia nigra of patients with Parkinson's disease (PD) does not occur evenly throughout the nucleus: the ventrolateral part of the substantia nigra degenerates more severely, whereas the medial part is relatively preserved. This pattern of nigral neuronal loss is compatible