Pathogenesis of myeloma bone disease
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G. David Roodman
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Article
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2009
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John Wiley and Sons
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English
β 150 KB
## Abstract Multiple myeloma (MM) is the most common cancer to involve bone with up to 90% of patients developing bone lesions. The bone lesions are purely osteolytic in nature and do not heal in the vast majority of patients. Up to 60% of patients develop pathologic fractures over the course of th