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Pathogenesis of head malformations in CD1 mice exposed in utero to VPA

✍ Scribed by Elena Menegola; Maria L. Broccia; Francesca Di Renzo

Book ID: 113875717
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 47 KB
Volume: 30
Category: Article
ISSN: 0890-6238
DOI: 10.1016/j.reprotox.2010.05.041

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## Abstract ## BACKGROUND Methanol causes axial skeleton and craniofacial defects in both CD‐1 and C57BL/6J mice during gastrulation, but C57BL/6J embryos are more severely affected. We evaluated methanol‐induced pathogenesis in CD‐1 and C57BL/6J embryos exposed during gastrulation in whole embryo