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Pathogenesis of acute myeloid leukaemia and inv(16)(p13;q22): a paradigm for understanding leukaemogenesis?

✍ Scribed by John T. Reilly


Book ID
108672917
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
331 KB
Volume
128
Category
Article
ISSN
0007-1048

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CBFB and MYH11 in inv(16)(p13q22) of acu
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## Abstract To gain a better understanding of the mechanism of chromosomal translocations in cancer, we investigated the spatial proximity between __CBFB__ and __MYH11__ genes involved in inv(16)(p13q22) found in patients with acute myeloid leukemia. Previous studies have demonstrated a role for sp