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Pathobiology of NPM-ALK and variant fusion genes in anaplastic large cell lymphoma and other lymphomas

✍ Scribed by Drexler, H G; Gignac, S M; von Wasielewski, R; Werner, M; Dirks, W G


Book ID
110054653
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
748 KB
Volume
14
Category
Article
ISSN
0887-6924

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## Abstract The t(2;5)(p23;q35) translocation results in the formation of a unique chimeric NPM‐ALK protein (p80). Expression of this protein is considered to be one of the clinical features of anaplastic large cell lymphoma (ALCL). Recently recognized as one clinical subtype of ALCL, the small cel