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Passive vaccination with a human monoclonal antibody: Generation of antibodies and studies for efficacy in Bacillus anthracis infections

✍ Scribed by Ulrich vor dem Esche; Maria Huber; Andrea Zgaga-Griesz; Roland Grunow; Wolfgang Beyer; Ulrike Hahn; Wolfgang G. Bessler

Book ID: 116569586
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 694 KB
Volume: 216
Category: Article
ISSN: 0171-2985
DOI: 10.1016/j.imbio.2010.12.001

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## Abstract Monoclonal antibody UJ13A radiolabelled with isotopes of iodine has been shown to selectively localize to human neuroblastoma xenografts. When ^131^I‐UJ13A conjugates were given to nude mice at high doses (100–150 μCi), tumours temporarily disappeared, only to regrow. No selection for n