Neural stem cells (NSCs) are primitive cells that are the "parent" cells of all the cells in the central nervous system (CNS). Their discovery in 1992 opened the door to a multitude of potential therapies and treatments to cure neurodegenerative diseases such as Parkinson's disease, multiple scleros
Passaging Protocols for Mammalian Neural Stem Cells in Suspension Bioreactors
โ Scribed by Arindom Sen; Michael S. Kallos; Leo A. Behie
- Book ID
- 109386377
- Publisher
- American Institute of Chemical Engineers
- Year
- 2002
- Tongue
- English
- Weight
- 141 KB
- Volume
- 18
- Category
- Article
- ISSN
- 8756-7938
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Inoculation and growth conditions for the large-scale expansion of mammalian neural stem cells (NSC) have been determined. We examined suspension culture bioreactors of murine NSC, and concluded that the oxygen level should be kept high (20%), and the osmolarity of the medium should be kept low (bel
## Abstract The clinical use of neural precursor cells (NPCs) for the treatment of neurological diseases, such as Parkinson's disease and Huntington's disease, requires overcoming the scarcity of these cells through controlled expansion. The main objective of the present study was to develop a larg