Dynamic changes in chromatin structure t
✍
E. Rampakakis; D. Di Paola; M.K. Chan; M. Zannis-Hadjopoulos
📂
Article
📅
2009
🏛
John Wiley and Sons
🌐
English
⚖ 223 KB
## Abstract Genome duplication relies on the timely activation of multiple replication origins throughout the genome during S phase. Each origin is marked by the assembly of a multiprotein pre‐replication complex (pre‐RC) and the recruitment of the replicative machinery, which can gain access to re