Mechanical Fingerprints of DNA Drug Comp
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Rupert Krautbauer; Stefan Fischerländer; Stephanie Allen; Hermann E. Gaub
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Article
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2002
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John Wiley and Sons
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English
⚖ 231 KB
We have investigated in detail the effects of different minor groove binders and intercalators on the mechanical properties of single DNA molecules under mechanical tension. It is known that individual double stranded DNA molecules show a highly cooperative overstretching transition and may be separ