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Particulate guanylate cyclase of skeletal muscle. Effects of Ca2+ and other divalent cations on enzyme activity

✍ Scribed by Steven N. Levine; Alton L. Steiner; H.Shelton Earp; Gerhard Meissner

Book ID
115735182
Publisher
Elsevier Science
Year
1979
Weight
694 KB
Volume
566
Category
Article
ISSN
0005-2744

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Effects of Ca2+and other divalent cation
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Slow muscle fibers were dissected from cruralis muscles of Rana esculenta and Rana pipiens. Isometric contractures were evoked by application of K(+)-rich Ringer's containing Ca2+, Ni2+, Co2+, Mn2+ or Mg2+. High (7.2 mmol/liter) external Ca2+ concentration raised, 0 Ca2+ lowered the K+ threshold. Re