Particular small size RNA and RNA fragments from different origins as tumor inducing agents inDatura stramonium
✍ Scribed by M. Beljanski; M. I. Aaron da Cunha
- Book ID
- 104738241
- Publisher
- Springer
- Year
- 1976
- Tongue
- English
- Weight
- 888 KB
- Volume
- 2
- Category
- Article
- ISSN
- 0301-4851
No coin nor oath required. For personal study only.
✦ Synopsis
Particular RNA fragments obtained by action of pancreatic ribonuclease on purified RNAs originating from species totally unrelated to Agrobacterium tumefaciens (Escherichia coli, rabbit, monkey) are capable of inducing the formation of transplantable tumorous tissue when introduced at wounded sites in inverted stems ofDatura stramonium maintained under axenic conditions on a medium containing auxin and kinetin. Reovirus RNA and a small size RNA (5-6 S) isolated from RNA bound RNA directed DNA polymerase from Escherichia coli also induced the appearance of tumorous tissues which grow on solid synthetic medium in the absence of auxin and kinetin.