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Particles in therapeutic protein formulations, Part 1: Overview of analytical methods

✍ Scribed by Sarah Zölls; Ruedeeporn Tantipolphan; Michael Wiggenhorn; Gerhard Winter; Wim Jiskoot; Wolfgang Friess; Andrea Hawe


Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
355 KB
Volume
101
Category
Article
ISSN
0022-3549

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The amount, identity, and size distribution of particles in parenteral therapeutic protein formulations are of immense interest due to potential safety and efficacy-related implications. In this communication, we describe the use of a flow cytometer equipped with forward- and side-scattering as well