Participation of the Entner–Doudoroff pathway in Escherichia coli strains with an inactive phosphotransferase system (PTS – Glc + ) in gluconate and glucose batch cultures

Utility of an Escherichia coli strain en

Utility of an Escherichia coli strain engineered in the substrate uptake system for improved culture performance at high glucose and cell concentrations: An alternative to fed-batch cultures

✍ Alvaro R. Lara; Luis Caspeta; Guillermo Gosset; Francisco Bolívar; Octavio T. Ra 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 248 KB 👁 2 views

## Abstract Overflow metabolism is an undesirable characteristic of aerobic cultures of __Escherichia coli__. It results from elevated glucose consumption rates that cause a high substrate conversion to acetate, severely affecting cell physiology and bioprocess performance. Such phenomenon typicall