Partialsynthesen von Cardenoliden und Cardenolid-Analogen. XI. Synthese von 3-(3β,14-Dihydroxy-5β,14β-androstan-17β-yl-methyl)but-2-en-4-olid, eines homologen 5β,14β-Cardenolids

Synthese von 4-[3β, 14-Dihydroxy-5β, 14β

Synthese von 4-[3β, 14-Dihydroxy-5β, 14β-androstan-17β-yl]-3-pyrrolin-2-on (Hothesimogenin). Partialsynthetische Versuche in der Reihe der Herzgifte, 11. Mitteilung

✍ Theodor W. Güntert; Horst H. A. Linde; Mohamed S. Ragab; Sigrid Spengel 📂 Article 📅 1978 🏛 John Wiley and Sons 🌐 German ⚖ 490 KB 👁 1 views

**Synthesis of 4‐[3β, 14‐Dihydroxy‐5β, 14β‐androstan‐17β‐yl]‐3‐pyrrolin‐2‐one (hothesimogenin)** We describe the synthesis of 4‐[3β, 14‐Dihydroxy‐5β, 14β‐androstan‐17β‐yl]‐3‐pyrrolin‐2‐one (24‐aza‐24‐desoxa‐digitoxigenin) **(7)**, starting from 3‐__O__‐acetyl‐digitoxigenin **(1)**.