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Partially Unfolded States of β2-Microglobulin and Amyloid Formation in Vitro†

✍ Scribed by McParland, Victoria J.; Kad, Neil M.; Kalverda, Arnout P.; Brown, Anthony; Kirwin-Jones, Patricia; Hunter, Michael G.; Sunde, Margaret; Radford, Sheena E.

Book ID
111902917
Publisher
American Chemical Society
Year
2000
Tongue
English
Weight
344 KB
Volume
39
Category
Article
ISSN
0006-2960

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Capillary electrophoresis investigation
Capillary electrophoresis investigation of a partially unfolded conformation of β2-microglobulin
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## Capillary electrophoresis investigation of a partially unfolded conformation of â 2 -microglobulin Dialysis-related amyloidosis is a disease in which partial unfolding of b 2 -microglobulin plays a key pathogenetic role in the formation of the amyloid fibrils. We have recently demonstrated that