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Partial trisomy 18q12, due to intrachromosomal duplication, is not associated with typical 18 trisomy phenotype

✍ Scribed by J. P. Fryns; L. Vinken; J. Marien; H. Berghe


Publisher
Springer
Year
1979
Tongue
English
Weight
160 KB
Volume
46
Category
Article
ISSN
0340-6717

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✦ Synopsis


Partial 18q12 trisomy, due to intrachromosomal duplication, was found in a severely mentally retarded boy. The finding of nonspecific dysmorphism in this patient demonstrates that trisomy of band 18q12 is accompanied by neither a full nor an incomplete 18 trisomy phenotype, indicating that this phenotype may be due solely to trisomy of the 18q11 band.