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Partial reduction in neural cell adhesion molecule (NCAM) in heterozygous mice induces depression-related behaviour without cognitive impairment

✍ Scribed by Monika Jürgenson; Anu Aonurm-Helm; Alexander Zharkovsky


Book ID
113506018
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
826 KB
Volume
1447
Category
Article
ISSN
0006-8993

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## Abstract In rodents, chronic stress induces long‐lasting structural and functional alterations in the hippocampus, as well as learning and memory impairments. The neural cell adhesion molecule (NCAM) was previously hypothesized to be a key molecule in mediating the effects of stress due to its r